Cell?line?development?or?CLD?is?among?the?most?expensive?and?time?consuming?parts?of
producing?a?new?biologic. 

Drug?developers?who?outsource?their?CLD?to?Sartorius?get?access?to?specialized?expertise?and?technology?and?benefit?from?predictable?performances?for?robust?clinical?and?commercial
?scalability. 

Over?the?last?15?years,?we?have?completed?more?than?300?client?projects?with?our?CHO?host ?cell?line. 

More?than?80?of?those?therapeutics?that?we?have?developed?are?currently?in?different?stages?of?the?clinical?trials,?and?we've?8?molecules?that?are?in?commercial?manufacturing,?approved ?for?market?use. 

To?meet?our?growing?customer?demands,?we?invested?in?a?new?6000?square?meter?facility?in?Ulm,?Germany.?We?have?moved?in?at?the?beginning?of?2020,?and?today?there?are?
approximately?120?staff?members?working?across?a?number?of?departments,?including?
product?development,?client?management,?and?laboratory?management. 

Let's?now?walk?through?our?CHO?CLD?process?directly?from?our?labs. 

 

We?have?improved?our?cell?line?development?service?through?automated?clone?ranking?and?
selection?of?single?cells?with?integrated?monoclonality?and?viability?assessment.?The?cell?
selector?increases?the?delivery?speed?from?DNA?to?research?cell?bank?from?14?weeks?to?just?
9?weeks?by?removing?the?need?for?multiple?cell?pools. 

Also,?implementing?automated?small-scale?fed?batch?helps?in?the?earlier?and?better
?selection?of?high?producer?clones?under?simulated?process?conditions. 

Additionally,?our?superior?scalable?technology?leads?to?high?productivity?of?protein?titers?of
?up?to?10?grams?per?liter?and?high?product?quality. 

Our?CHO?CLD?technology?delivers?a?product?with?scalable?performances?up?to?
2,000 Liter?bioreactor. 

With?the?experience?of?more?than?300?successful?projects?and?15?years?of?technical?and?
regulatory?expertise,?we?help?our?clients?get?it?right?the?first?time.?Our?customers?do?not?have?to?pay?for?royalties?or?clinical?milestones. 

Finally,?we?provide?a?dedicated?team?of?client?managers?a?single?point?of?contact?throughout?the?CLD?process,?facilitating?the?flow?of?information?and?helping?drug?developers?to?reach?
industrialization?faster.